Erythema multiforme
☆ Tamin'ny valin'ny Stiftung Warentest 2022 avy any Alemaina, ny fahafaham-pon'ny mpanjifa amin'ny ModelDerm dia ambany kely noho ny fifampidinihana telemedicine karama.
Erythema multiforme minor ― Mariho fa ny ivon'ny fery dia mety hifoka.
urticaria koa dia azo raisina ho toy ny diagnosy différence.
References
Erythema multiforme (EM) dia toe-javatra ahitana tasy mitovitovy amin'ny kendrena miavaka amin'ny hoditra sy ny mucous membrane noho ny fihetsiky ny hery fiarovana. Na dia ateraky ny areti-mifindra matetika aza, indrindra fa ny virosy herpes simplex (HSV) , na fanafody sasany, dia mbola tsy fantatra ny antony amin'ny tranga maro. Ny fitsaboana EM acute dia mifantoka amin'ny fanalefahana ny soritr'aretina amin'ny fampiasana crème misy steroïde na antihistamines. Ny fitantanana EM miverimberina dia mahomby indrindra rehefa mifanaraka amin'ny marary tsirairay. Ny fomba fiasa voalohany dia misy fitsaboana am-bava sy topical. Anisan'izany ny corticosteroids sy ny fanafody antiviral. Ny fitsaboana topical dia misy crème steroïde matanjaka sy vahaolana ho an'ny mucous membranes voakasika. Ho an'ireo marary tsy manaiky antiviral, ny safidy andalana faharoa dia misy fanafody manafoana ny hery fiarovana, antibiotika, anthelmintika ary antimalaria.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Amin'ny toe-javatra maro, ny erythema multiforme malemy dia miala ho azy ao anatin'ny 2 na 4 herinandro. Ny aretin'i Stevens-Johnson, aretina mafy mihatra amin'ny mucous membrane, dia mety haharitra hatramin'ny 6 herinandro. Ny steroïde dia tsy soso-kevitra amin'ny tranga malemy. Tsy azo antoka raha tokony hampiasaina amin'ny erythema multiforme mafy ny steroïde satria tsy misy fikarohana mazava avy amin'ny fanadihadiana natao kisendrasendra izay manondro hoe iza amin'ireo ankizy no mahazo tombony amin'ity fitsaboana ity.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Asehoy ny trangan'ny erythema multiforme (EM) am-bava vokatry ny TMP/SMX , mampiseho fery am-bava sy molotra tsy misy fery amin'ny hoditra. Izany dia manamafy fa ilaina ny manavaka azy amin'ny aretina fery amin'ny vava. Ny marary dia nahazo fitsaboana symptomatic sy takelaka prednisolone, izay nitarika ho amin'ny fanatsarana taorian'ny fampitsaharana ny fitsaboana TMP / SMX.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme dia fanehoan-kevitra mahakasika ny hoditra ary indraindray ny mucosa, ateraky ny hery fiarovana. Amin'ny ankapobeny dia mipoitra toy ny lesoka mitovitovy amin'ny kendrena izy io, izay mety ho toa mitoka-monina, miverimberina, na maharitra. Matetika ireo ratra ireo dia misy fiantraikany amin'ny tendrony, indrindra ny ety ivelany. Ny antony lehibe indrindra dia ny aretina toy ny herpes simplex virus sy ny Mycoplasma pneumoniae, ary koa ny fanafody sasany, ny vaksiny ary ny aretina autoimmune. Ny fanavahana ny erythema multiforme amin'ny urticaria dia miankina amin'ny faharetan'ny fery; erythema multiforme ny lesoka dia mijanona mandritra ny fito andro fara-fahakeliny, fa ny fery urticaria matetika dia levona ao anatin'ny iray andro. Na dia mitovitovy aza, dia zava-dehibe ny manavaka ny erythema multiforme amin'ny aretin'i Stevens-Johnson mahery kokoa, izay mazàna dia macules erythematous na purpuric miparitaka be miaraka amin'ny blisters. Ny fitantanana ny erythema multiforme dia mitaky fanamaivanana soritr'aretina miaraka amin'ny steroïde topical na antihistamines ary ny famahana ny antony fototra. Ho an'ny tranga miverimberina mifandray amin'ny viriosy herpes simplex, dia ilaina ny fitsaboana antiviral prophylactic. Ny fidiran'ny mucosal mafy dia mety hilaina any amin'ny hôpitaly amin'ny fluid intravenous sy fanoloana electrolyte.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Ny toe-javatra dia miovaova avy amin'ny maimaika malefaka sy voafetra ho amin'ny endrika mahery vaika izay mamono ny aina fantatra amin'ny anarana hoe erythema multiforme major izay misy koa ny mucous membranes. Ny fanafihana ny mucous fonontselan'ny na ny fisian'ny bullaes dia famantarana lehibe ny hamafin'ny.
- Erythema multiforme minor: lasibatra mahazatra na mitsangana, papules edematous zaraina acraly
Ny endrika malefaka dia matetika miseho amin'ny mangidihidy malefaka (fa mety ho mafy be ny fihintsanana), tasy mavokely-mena, mirindra symmetrika ary manomboka eo amin'ny tendrony. Ny famahana ny maimaika ao anatin'ny 7-10 andro dia mahazatra amin'ity endrika aretina ity.
- Erythema multiforme major: lasibatra mahazatra na mitsangana, papules edematous mizara amin'ny acraly miaraka amin'ny fidiran'ny mucous membrane iray na maromaro. Ny epidermal detachment dia ahitana latsaky ny 10% amin'ny velaran'ny vatana manontolo.
○ Fitsaboana - Fanafody OTC
Raha miaraka amin'ny tazo (fitomboan'ny hafanan'ny vatana) dia asaina manatona hopitaly haingana.
Tokony hatsahatra ny fanafody ahiana. (oh: antibiotika, fanafody miady amin'ny inflammatoire tsy steroidal)
Antihistamines am-bava toy ny cetirizine sy loratadine ho an'ny mangidihidy.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]